Tissue preparation is the step in spatial transcriptomics that can determine whether an experiment succeeds or fails before the sample ever reaches the instrument. Getting fixation, sectioning, and ...

Revealing how proteins and end products of biological activity (metabolites) change within specific tissue functional units during development or in response to environmental factors is beneficial for ...

3D spatial biology addresses one of the field's most persistent blind spots: the loss of depth. Most spatial transcriptomics platforms generate data from a single tissue section, a thin slice ...

Histology, the study of tissues at a microscopic level, unveils the intricate architecture of biological structures within organisms. Utilizing specialized staining and imaging techniques, histology ...

The two main fixation formats used by researchers are formalin fixation followed by paraffin embedding (FFPE) or snap-frozen in liquid nitrogen (referred to as Fresh Frozen or FF). There is less of a ...